Hooman Kamel, M.D. is the Director of the Clinical and Translational Neuroscience Unit (CTNU) at the Brain and Mind Research Institute.
The CTNU has published research in journals such as New England Journal of Medicine, JAMA, Circulation, and Annals of Neurology. Dr. Kamel involves crucial participation from students, residents, and fellows in all publications and research studies, passing on his neurological experience to the next group of residents. Dr. Kamel has substantial experience working with patients affected by stroke and neurological diseases. He now leads an active research program through CTNU, with studies in research areas including vascular neurology, stroke, and critical care. Browse Dr. Kamel's Recent Publications.
Learn about the CTNU Fellowship Program to work with Dr. Kamel or other CTNU principal investigators.
CTNU Mission
Dr. Kamel is a neurologist and clinical scientist whose research focuses on stroke prevention. He is currently investigating novel associations between cardiac arrhythmias and ischemic stroke.
Discovering new links between heart disease and stroke may have important near-term implications for improving stroke prevention, because several approved drugs have proven efficacy in treating currently recognized sources of cardiac embolism.
Dr. Kamel's work spans the clinical and translational neuroscience spectrum. The CTNU research program relies on a combination of state-level administrative claims data to study disease at a population level, detailed clinical and physiological data from large-scale epidemiological studies, and exploratory biomarker studies in carefully selected cohorts of patients with stroke. This research program was previously funded by a Scientist Development Grant from the American Heart Association and a K23 award from the NIH, and is currently funded by several NIH grants.
Research Goals
To identify novel risk factors for stroke and conduct randomized clinical trials of new therapeutic strategies to address those risk factors.
CTNU Achievements
- Identified a novel association between atrial cardiopathy and ischemic stroke.
- Identified novel imaging techniques for identifying occult atherosclerotic plaque as a cause of stroke.
- Demonstrated that the risk of thrombotic events remains elevated beyond the traditional 6-week postpartum period, and persists for at least 12 weeks after labor and delivery.
Joint Appointments
Dr. Kamel's primary appointment is in the Department of Neurology, and his secondary appointment is in the BMRI.
Neurological Study Collaborations
Dr. Kamel's past collaborations have included studies on a wide array of neurological topics with the following researchers:
Costantino Iadecola, Richard Devereux, Peter Okin, Babak Navi, Matthew Fink, Ajay Gupta, Ankur Pandya, Amy Kuceyeski, Ashish Raj.