Academic Year 2020

Drs. Anna and Adam Orr (PIs)

Daedalus Fund for Innovation of Weill Cornell Medicine BP 214689-01
Site-Specific Blockers of Mitochondrial FreeRadicals for Therapeutic Intervention in Neurodegenerative Diseases

Marilena D'Aurelio (PI)
National Institute of Neurological Disorders and Stroke 1R21NS118233-01A1
Modulation of intermediate metabolism, a new therapeutic approach for mitochondrial encephalomyopathies

Margaret Ross  (PI) 

University of Michigan 1 U54 NS117170-01 PROJECT 1
Epilepsy Multiplatform Variant Prediction (EpiMVP)

Jacqueline Burre (PI)
National Institute of Neurological Disorders & Stroke 1R01NS121077-01
The role of VAMP2 in alpha-synuclein function and pathology

Makoto Ishii (PI)
National Institute on Aging 1R01AG070868-01
Hypothalamic and metabolic dysfunction in Alzheimer's disease

Giuseppe Faraco (PI)
Cure Alzheimer's Fund CAF211776-01
Gut microbiota, endothelial dysfunction and tau-mediated cognitive impairment

Subhash Sinha (PI)
Cure Alzheimer's Fund CAF 212347-01
vHTS for CD33 inhibitors

Giovanni Manfredi (PI) 
National Institute of Neurological Disorders & Stroke 1R01NS120477-01 1R35NS122209-01
Raloxifene-based therapy in neuro degenerative diseases

Natalia De Marco Garcia (PI)
National Institute of Mental Health 1R01MH125006-01 
GABAergic Interneuron Dysfunction in Developing Cortical Circuits Underlying Autism Spectrum Disorders

Li Gan (PI) 
Rainwater Charitable Foundation RCF190078-01 
Project 1: Targeting microglial-mediated toxicity treat tauopathy

Giovanni Manfredi (PI)  
National Institute of Neurological Disorders & Stroke 3R01NS112672-02S1 
The role of the mitochondrial protein dimer CHCHD2/10 in health and disease

Margaret Ross  (PI) 
Tri-Institutional Stem Cell Initiative (Weill Cornell) 2019-022 
MOLECULAR DETERMINANTS OF NEURAL STEM CELL LINEAGE PROGRESSION AND LIFESPAN IN MICE AND HUMANS

Li Gan (PI) 
The JPB Foundation JPB194610-02
Targeting maladaptive innate immune response to treat PD

Alicia Che (PI) 
National Institute of Neurological Disorders & Stroke 1 K99 NS114166-01
Maturation of somatosensory circuits for social behaviors

Ping Zhou (PI)
National Institute of Neurological Disorders & Stroke  2R56NS067078-11A1
Role of Prohibitin in Ischemic Brain Injury

Giovanni Manfredi (PI) 
The Friedreich’s Ataxia Research Alliance (FARA)
Mitochondrial integrated stress response in FA cardiomyopathy

Nicholas Schiff (PI)
James S. McDonnell Foundation JSMF 2020-1412
COVID-19 Consortium for Recovery of Consciousness

Virginia Pickel (PI)
NATIONAL INSTITUTES OF HEALTH 1S10OD026974-01A1
TRANSMISSION ELECTRON MICROSCOPE

Natalia De Marco Garcia (PI) 
National Institute of Neurological Disorders & Stroke 1 R01 NS116137-01A1 
A Circuit Mechanism for the Development of Cortico-cortical Connectivity

Anna Orr (PI) 
National Institute of Aging 1R01AG068091-01
Mitochondrial Complex III Free Radicals in Dementia-Related Proteinopathy and Neuroinflammation

Wenjie Luo (PI)
National Institute on Aging 1R01AG064239-01A1 
Essential roles of DAP12 in tau metabolism and inflammation in Alzheimer's disease

Anna Orr (PI) 
National Institute of Neurological Disorders & Stroke 1RF1NS118569-01
Defining the Effects of Astrocytic TDP-43 Dysregulation on Hippocampal Function

Natalia De Marco Garcia (PI)
Irrina T. Hirshl Trust
Irrina T. Hirschl Career Scientist Award

Giovanni Manfredi (PI)
Christina Foundation
THE ROLE OF CALCIUM DYSREGULATION IN FA

Natalia De Marco Garcia (PI)
Brain Research Foundation BRFSG-2020-03
A Circuit Mechanism for the Development of Cortico-cortical Connectivity

Jacqueline Burre (PI)
National Institute of Neurological Disorders & Stroke 1R01NS113960-01A1
The impact of synaptic vesicle-binding of alpha-synuclein on neuron function and neuropathology

Margaret Ross (PI)
Tri-Institutional Stem Cell Initiative (Weill Cornell) 2019-022
MOLECULAR DETERMINANTS OF NEURAL STEM CELL LINEAGE PROGRESSION AND LIFESPAN IN MICE AND HUMANS

Makoto Ishii (PI)
The Alzheimer's Association AARG-20-681013
Calcium dysregulation and hypothalamic dysfunction in Alzheimer's disease

Kevin McAvoy (PI)
National Institute of Neurological Disorders & Stroke 1F32NS116151-01
Defining the functional role of astrocyte-derived lactate

Jonathan Baker (PI)
National Institute of Neurological Disorders & Stroke 1R01NS111019-01A1
Central thalamic deep brain stimulation to regulate arousal and cognition

Marilena D'Aurelio (PI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases 1R01AR076029-01A1
Metabolic remodeling of skeletal muscle in mitochondrial myopathies

Esteban Fridman (PI)
National Institute of Neurological Disorders & Stroke 1R21NS109697-01A1
Evaluation of pharmacologically-induced changes in excitatory glutamatergic neurotransmission of severe TBI patients

Hagen Tilgner (PI)
National Institute of General Medical Sciences 3R01GM135247-02S1
Cross-species conservation of cell-type and single-cell specific isoform expression

Timothy Vartanian (PI)
National Multiple Sclerosis Society RG-1908-34822
Defining ancestry associated B-cell inflammation in treatment naïve

Makoto Ishii (PI)
BrightFocus Foundation A2020363S
Circulating immunometabolic factors in Alzheimer's disease

Jennifer Linden (PI)
Myelin Repair Foundation SRA 215280-01
Evaluation of Microglia Derived Extracellular Vesicles in MS Patients with Chronic Active Lesions

Tim Vartanian (PI)
National Institute of Allergy and Infectious Diseases 1R21AI144819-01A1
Determining Enhanced Inflammatory B cell Function in African Americans with MS

Josef Anrather (PI)
Leducq Foundation 19CVD01
Stroke IMPaCT (Stroke Immune Mediated Pathways and Cognitive Trajectory)

Sung Ji Ahn (PI)
American Heart Association 20POST35120063
Pathological tau and neurovascular dysfunction

Weill Cornell Medicine Feil Family Brain & Mind Research Institute 407 E 61st St New York, NY 10065 Phone: (646) 962-8277 Fax: (646) 962-0535