In a study published in Science 12 April 2019, Dr. Conor Liston and teams of scientists have identified that ketamine-induced changes in the brain are responsible for the remission of depression in mice. These findings may help researchers develop interventions that promote lasting remission of depression in humans.
For more information:
https://news.weill.cornell.edu/news/2019/04/study-shows-how-ketamine-reverses-depression—and-how-its-benefits-could-be-extended
https://news.cornell.edu/stories/2019/04/ketamines-short-term-relief-depression-could-be-extended-researchers-find