Mar 6 2020 - 12:00pm to 1:00pm
Location: Feil Family Research Building
“A Pediatric Epilepsy Learning Health Care System” Zachary Grinspan, M.D., M.S. Pediatric Epilepsy Program Director Associate Health Care Policy & Research and Pediatrics Professor Weill Cornell Medicine (WCM) NewYork-Presbyterian (NYP) Hospital
Mar 5 2020 - 4:00pm to 5:00pm
Location: Weill Auditorium
Fluid homeostasis is a vital function that regulates the balance between water and sodium. When this balance shifts in one direction, the brain detects the changes and triggers appetite to drive water or sodium intake for compensation. Defining the neural logic of these processes is critical for understanding brain function underlying normal and abnormal appetite. Our goal is to understand how the brain processes internal state information and peripheral signals to regulate goal-oriented...
Feb 28 2020 - 12:00pm to 1:00pm
Location: Feil Family Research Building
"Stabilization of Munc18-1 Function via Target-Specific Pharmacological Chaperones Identified Through an in Silico Screen” Debra Abramov Tri-institutional M.D.-Ph.D. Candidate Weill Cornell Medicine (WCM) BMRI Burre Laboratory
Feb 27 2020 - 4:00pm to 5:00pm
Location: Weill Auditorium
Richard Youle Ph.D. Surgical Neurology Branch, NINDS, NIH, Bethesda, MD USA PINK1 and Parkin, both mutated in familial PD, normally work intimately together to initiate autophagy of impaired mitochondria. When mitochondria are damaged, Pink1 senses the damage and accumulates specifically on the outer membrane of damaged mitochondria where it phosphorylates ubiquitin chains. These phosphorylated ubiquitin chains on the outer mitochondrial membrane bind to cytosolic Parkin and activate Parkin’s...
Feb 21 2020 - 12:00pm to 1:00pm
Location: Feil Family Research Building
"A System Biology Analysis of Human Genomes Points to Key Pathways Conferring Risk of Spina Bifida" Vanessa Aguiar-Pulido, Ph.D. Neuroscience Instructor Weill Cornell Medicine (WMI) BMRI Neurogenetics Center
Feb 20 2020 - 4:00pm to 5:00pm
Location: Weill Auditorium
Jie Shen Ph.D., Professor of Neurology, Harvard Medical School The major research interests of the Shen laboratory focus on elucidation of the pathogenic mechanisms of Alzheimer’s and Parkinson’s diseases. Specifically, a multidisciplinary approach is employed to investigate the molecular and cellular mechanisms underlying pathologic degeneration of specific neuronal populations. 1) Xia et al. Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer’s disease. Neuron...
Feb 14 2020 - 12:00pm to 1:00pm
Location: Feil Family Research Building
"Paraventricular thalamus provides a synaptic break on limbic CRF neurons to blunt risky alcohol drinking and anxiety" Olivia Brooke Levine Neuroscience Ph.D. candidate Pleil Laboratory Department of Pharmacology WCM, New York, NY
Feb 7 2020 - 12:00pm to 1:00pm
Location: Feil Family Research Building
"An Update on Rapid Eye Movement (REM) Behavior: Research and Treatment" Daniel A. Barone, F.A.A.S.M., M.D. Associate Center for Sleep Medicine Medical Director Assistant Clinical Neurology Professor Weill Cornell Medicine
Jan 31 2020 - 12:00pm to 1:00pm
Location: Feil Family Research Building
"Neuropsychological Evaluation for Cognitive Disorder" Lisa D. Ravdin, Ph.D. Associate Neuropsychology Professor and Director Weill Cornell Medicine Neurology
Jan 30 2020 - 4:00pm to 5:00pm
Location: A-250 Estabrook Lecture Hall
Frank Polleux, Ph.D., Columbia University neuroscience professor, will present evidence characterizing the function of mitochondria, endoplasmic reticulum and ER-mitochondria contact in dendrites and axons of cortical pyramidal neurons. This will include characterization of mitochondria function regulating presynaptic neurotransmitter release through their ability to uptake Ca2+, Pdzd8-dependent ER-mitochondria contacts regulating synaptically-evoked dendritic Ca2+ dynamics and in vivo...